The proposed program will involve both theorists and experimentalists interested in physics underground. The intent will be to allow this community to further define its science goals and how those goals might influence the design and operations of a deep US laboratory. The program will focus on topics such as the synergy between accelerator and astrophysical long-baseline tests of the neutrino mass; next generation particle dark matter searches; the possibility of precision long-baseline neutrino oscillation experiments to measure CP violation; the construction of very large proton decay detectors, and whether those detectors could also be exploited to measure the neutrino "light curves" of galactic supernovae; the need for low-level counting facilities for generic detector development; and the possibility of a low-energy underground accelerator for measuring nuclear astrophysics cross sections in the Gamow peak by inverse kinematics.