Focus questions for the INT Program, "Quantitative Large-Amplitude Shape Dynamics" 1. What are the needs for the applications of fission? 2. What accuracy and precision can we now achieve in measurements related to fission? 3. What are our short- and medium-term experimental needs? 4. What can we learn about fission dynamics from reactions induced by particle transfer and by inelastic scattering? 5. How reliable are the theories of collective dynamics based on the adiabatic HFB approximation, the time-dependent HFB, and other approaches? 6. Is the WKB an adequate approximation for subbarrier tunneling? 7. What are the roles of statistical vs inertial dynamics in the descent from the fission barrier to scission? 8. What is the present status of measuring fission lifetimes? 9. How can one gain insight into dynamics around the barrier from simplified many-body models? 10. What are the limits of validity of statistical decay models? 11. Can we improve models of trans-target production in deep inelastic scattering? 12. What is the dynamic evolution of dinuclear systems leading to quasi-fission? 13. What are the best ways to measure fusion probabilities? 14. How does weak binding of projectile or target affect the fusion reaction? 15. How well do we understand deep subbarrier fusion? 16. Is fission recycling a significant contributor to r-process nucleosynthesis? 17. What phenomenology-based codes provide the most reliable information for r-process simulations??